Apligraf, a skin substitute developed by Organogenesis, Inc., is cultured from human dermal cells (fibroblasts), and epidermal cells (keratinocytes). The fibroblasts are introduced to a collagen medium, which they inhabit and restructure.
Scenes from the clean rooms at Organogeneis: cryopreservation tanks.
Keratinocytes are then added on top to make the epidermis. Through exposure to air, the epidermis formsthe final protective layer. The illustration shows the formal similarities of Apligraf and human skin.
Flesh for sale: Integra.
, fresh off the assembly line and into handy, nonthreatening foil for the rest of its two-year shelf life. (Refrigeration recommended, though not required.)
Fresh off the assembly line and into handy, nonthreatening foil for the rest of its two-year shelf life. (Refrigeration recommended, though not required.)
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